Emerging Biological Therapies in Severe Eosinophilic Asthma
نویسندگان
چکیده
منابع مشابه
Emerging therapies for severe asthma
Many patients with asthma have poorly controlled symptoms, and particularly for those with severe disease, there is a clear need for improved treatments. Two recent therapies licensed for use in asthma are omalizumab, a humanized monoclonal antibody that binds circulating IgE antibody, and bronchial thermoplasty, which involves the delivery of radio frequency energy to the airways to reduce air...
متن کاملEosinophilic bioactivities in severe asthma
Asthma is clearly related to airway or blood eosinophilia, and asthmatics with significant eosinophilia are at higher risk for more severe disease. Eosinophils actively contribute to innate and adaptive immune responses and inflammatory cascades through the production and release of diverse chemokines, cytokines, lipid mediators and other growth factors. Eosinophils may persist in the blood and...
متن کاملEmerging therapies in severe sepsis.
Context: Activation of the coagulation system and depletion of endogenous anticoagulants are frequently found in patients with severe sepsis and septic shock. Diffuse microthrombus formation may induce organ dysfunction and lead to excess mortality in septic shock. Antithrombin III may provide protection from multiorgan failure and improve survival in severely ill patients. Objective: To determ...
متن کاملSevere eosinophilic asthma: a roadmap to consensus.
Affiliations: Dept of Pulmonary Medicine, Mainz University Hospital, Mainz, Germany. Dept of Respiratory Medicine, Université Paris-Sud, Paris, France. Dept of Respiratory Medicine and Allergology, Skåne University Hospital, Lund, Sweden. Dept of Respiratory Medicine, Aix-Marseille University, Marseille, France. Dept of Respiratory Medicine, Queen’s University Belfast, Belfast, UK. Nuffield Dep...
متن کاملMepolizumab (Nucala) For Severe Eosinophilic Asthma.
Mepolizumab (Nucala) for severe eosinophilic asthma.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pulmonary Therapy
سال: 2016
ISSN: 2364-1754,2364-1746
DOI: 10.1007/s41030-016-0019-x